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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1221749Generated: October 25, 2026

Dimethyl Sulfoxide → 2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)-5-(1-(tetrahydro-2H-pyran-4-yl)cyclopropyl)thiazolo[5,4-b]pyridine

https://huagongshe.com/reaction/1221749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantTetrahydrofuranHCID 8028—
ReactantIodide IonHCID 30165—
ReactantTrimethylsulfoxoniumHCID 74499—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)-5-(1-(tetrahydro-2H-pyran-4-yl)vinyl)thiazolo[5,4-b]pyridineHCID 67112136—
Product2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)-5-(1-(tetrahydro-2H-pyran-4-yl)cyclopropyl)thiazolo[5,4-b]pyridineHCID 67111805—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-413cfdbd24e14f598e139240fde49a3c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)