Dimethyl Sulfoxide → 2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)-5-(1-(tetrahydro-2H-pyran-4-yl)cyclopropyl)thiazolo[5,4-b]pyridine

HRID 1221749노트

반응식

[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:32][S+:33]([CH3:34])([CH3:35])=[O:36].[CH3:37][C:38]([CH3:39])([O-:40])[CH3:41].[CH3:48][S:49]([CH3:50])=[O:51].[I-:31].[K+:42].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:30])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22](=[CH2:23])[CH:24]5[CH2:25][CH2:26][O:27][CH2:28][CH2:29]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1>>[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:30])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22]5([CH:24]6[CH2:25][CH2:26][O:27][CH2:28][CH2:29]6)[CH2:23][CH2:32]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1