Hydrochloric Acid → Hydrochloric Acid

HRID 1221792Notes

Reaction equation

HRID 1221792 reaction equation
[ClH:1].[F:8][c:9]1[cH:10][cH:11][c:12]([C:15](=[O:16])[NH:17][c:18]2[cH:19][cH:20][c:21]([F:41])[c:22]([C:24]34[N:25]=[C:26]([NH:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[S:27][CH2:28][CH:29]3[CH2:30][O:31][CH2:32]4)[cH:23]2)[n:13][cH:14]1.[O:2]1[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1>>[ClH:1].[F:8][c:9]1[cH:10][cH:11][c:12]([C:15](=[O:16])[NH:17][c:18]2[cH:19][cH:20][c:21]([F:41])[c:22]([C:24]34[N:25]=[C:26]([NH2:33])[S:27][CH2:28][CH:29]3[CH2:30][O:31][CH2:32]4)[cH:23]2)[n:13][cH:14]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 66861447tert-butyl 7a-(5-(5-fluoropicolinamido)-2-fluorophenyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-ylcarbamate

Product 2

HCID 313Hydrochloric AcidHCID 57475760N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide

Sources & evidence

ORD record
ord-b31fb6303aa646a0806f303e903fe8d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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