1-Methylpiperazine → 5-(2-Benzyl-2H-indazol-6-yl)-7-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine

HRID 1222439Notes

Reaction equation

HRID 1222439 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[n:9][c:10]2[cH:11][c:12](-[c:17]3[cH:18][c:19](-[c:27]4[cH:28][cH:29][c:30]([CH2:33][Br:34])[cH:31][cH:32]4)[n:20]4[n:21][cH:22][n:23][c:24]([NH2:26])[c:25]34)[cH:13][cH:14][c:15]2[cH:16]1.[CH3:35][N:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[n:9][c:10]2[cH:11][c:12](-[c:17]3[cH:18][c:19](-[c:27]4[cH:28][cH:29][c:30]([CH2:33][N:39]5[CH2:38][CH2:37][N:36]([CH3:35])[CH2:41][CH2:40]5)[cH:31][cH:32]4)[n:20]4[n:21][cH:22][n:23][c:24]([NH2:26])[c:25]34)[cH:13][cH:14][c:15]2[cH:16]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 693032915-(2-benzyl-2H-indazol-6-yl)-7-(4-bromomethyl-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine

Product 1

HCID 585296715-(2-Benzyl-2H-indazol-6-yl)-7-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine

Sources & evidence

ORD record
ord-59d379c53dce4d6a878ac5326c2447e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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