Toluene → N-Cyclopropylmethyl-6-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide
Reaction equation
[CH3:10][O:11][C:12]([c:13]1[cH:14][n:15][c:16]([O:19][CH2:20][c:21]2[c:22](-[c:28]3[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]3)[n:23][o:24][c:25]2[CH2:26][OH:27])[cH:17][cH:18]1)=[O:35].[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[NH2:5][CH2:6][CH:7]1[CH2:8][CH2:9]1.[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1>>[NH:5]([CH2:6][CH:7]1[CH2:8][CH2:9]1)[C:12](=[O:11])[c:13]1[cH:14][n:15][c:16]([O:19][CH2:20][c:21]2[c:22](-[c:28]3[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]3)[n:23][o:24][c:25]2[CH2:26][OH:27])[cH:17][cH:18]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-329539b077164582a92eee227061493d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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