HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1223300Generated: November 3, 2026
Water → 2-(4-(1,4-Dimethylpiperidin-4-yl)phenylamino)-5-fluoro-6-(3-phenyl-1-oxa-2,7-diazaspiro[4.5]dec-2-en-7-yl)nicotinamide
https://huagongshe.com/reaction/1223300
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-Phenyl-1-oxa-2,7-diazaspiro[4.5]dec-2-ene | HCID 56934460 | — |
| Reactant | 6-Chloro-2-(4-(1,4-dimethylpiperidin-4-yl)phenylamino)-5-fluoronicotinamide | HCID 57489656 | — |
| Product | 2-(4-(1,4-Dimethylpiperidin-4-yl)phenylamino)-5-fluoro-6-(3-phenyl-1-oxa-2,7-diazaspiro[4.5]dec-2-en-7-yl)nicotinamide | HCID 49847285 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
|---|
| ORD ID | ord-d968966545b349ee8bb1c28b6b7b502a |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
|---|
