Trifluoroacetic acid → Methyl 4-(pyrrolidin-2-ylmethoxy)benzoate

HRID 1223313Notes

Reaction equation

HRID 1223313 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH3:22])[cH:23][cH:24]2)[CH2:10][CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31]>>[NH:8]1[CH:9]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH3:22])[cH:23][cH:24]2)[CH2:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 73241637Tert-butyl 2-[(4-methoxycarbonylphenoxy)methyl]pyrrolidine-1-carboxylate

Product 1

HCID 73241625Methyl 4-(pyrrolidin-2-ylmethoxy)benzoate

Sources & evidence

ORD record
ord-96ba2ea1aefc42078b48281f9b5de5bb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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