Dichloromethane → 1-(2-(4-Aminopiperidin-1-yl)-2-oxoethyl)-3,3-diphenylpiperidin-2-one

HRID 1223480Notes

Reaction equation

HRID 1223480 reaction equation
[CH2:44]([Cl:45])[Cl:46].[O:1]=[C:2]1[N:3]([CH2:20][C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([NH:29][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:27][CH2:28]2)[CH2:4][CH2:5][CH2:6][C:7]1([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1.[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43]>>[O:1]=[C:2]1[N:3]([CH2:20][C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([NH2:29])[CH2:27][CH2:28]2)[CH2:4][CH2:5][CH2:6][C:7]1([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67443748HCID 67443748, compound

Product 1

HCID 673590361-(2-(4-Aminopiperidin-1-yl)-2-oxoethyl)-3,3-diphenylpiperidin-2-one

Sources & evidence

ORD record
ord-6787bc96f2894125a14101ac805bff58
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…