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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1223581Generated: October 31, 2026

Tetrahydrofuran → 4-(4-Ethoxy-2,3-difluorophenyl)-1-pentylcyclohexanol

https://huagongshe.com/reaction/1223581

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1-BromopentaneHCID 8057—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant1-Ethoxy-2,3-DifluorobenzeneHCID 2782928—
ReactantMagnesiumHCID 5462224—
Reactant4-(4-Ethoxy-2,3-difluorophenyl)cyclohexanoneHCID 11161121—
ReactantButyllithiumHCID 178418339—
Product4-(4-Ethoxy-2,3-difluorophenyl)-1-pentylcyclohexanolHCID 11324866—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-1d39b610afb8496f8242fa000ad2ff1e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)