Tetrahydrofuran → 4-(4-Ethoxy-2,3-difluorophenyl)-1-pentylcyclohexanol
Reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:26]([O:27][c:28]1[cH:29][cH:30][cH:31][c:32]([F:33])[c:34]1[F:35])[CH3:36].[CH2:37]([Li:38])[CH2:39][CH2:40][CH3:41].[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH2:8]([CH3:9])[O:10][c:11]1[c:12]([F:25])[c:13]([F:24])[c:14]([CH:17]2[CH2:18][CH2:19][C:20](=[O:23])[CH2:21][CH2:22]2)[cH:15][cH:16]1.[Mg:7].[O:42]1[C:43]2([CH2:44][CH2:45][C:46](=[O:47])[CH2:48][CH2:49]2)[O:50][CH2:51][CH2:52]1>>[CH2:2]([CH2:3][CH2:4][CH2:5][CH3:6])[C:20]1([OH:23])[CH2:19][CH2:18][CH:17]([c:14]2[c:13]([F:24])[c:12]([F:25])[c:11]([O:10][CH2:8][CH3:9])[cH:16][cH:15]2)[CH2:22][CH2:21]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-1d39b610afb8496f8242fa000ad2ff1e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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