Dichloromethane → N-[6-(2,3-difluorophenyl)-2-sulfanylideneazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:51][CH2:52][Cl:53].[F:8][c:9]1[c:10]([CH:16]2[CH2:17][CH2:18][CH:19]([NH:24][C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[C:20](=[S:23])[NH:21][CH2:22]2)[cH:11][cH:12][cH:13][c:14]1[F:15].[O:32]=[c:33]1[n:34]([CH:42]2[CH2:43][CH2:44][N:45]([C:48]([Cl:49])=[O:50])[CH2:46][CH2:47]2)[c:35]2[c:36]([n:37][cH:38][cH:39][cH:40]2)[nH:41]1>>[F:8][c:9]1[c:10]([CH:16]2[CH2:17][CH2:18][CH:19]([NH:24][C:25](=[O:31])[N:45]3[CH2:44][CH2:43][CH:42]([n:34]4[c:33](=[O:32])[nH:41][c:36]5[c:35]4[cH:40][cH:39][cH:38][n:37]5)[CH2:47][CH2:46]3)[C:20](=[S:23])[NH:21][CH2:22]2)[cH:11][cH:12][cH:13][c:14]1[F:15]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-7b5b0abd3dfd4bab9c0d9db2fe6e95d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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