Tetrahydrofuran → N-(4-(Dipropylphosphoryl)phenyl)-2-iodo-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
Reaction equation
[CH2:1]([CH2:2][CH3:3])[P:4](=[O:5])([CH2:6][CH2:7][CH3:8])[c:9]1[cH:10][cH:11][c:12]([NH2:15])[cH:13][cH:14]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[Cl:16][c:17]1[c:18]2[n:19][cH:20][n:21]([CH:27]3[O:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[c:22]2[n:23][c:24]([I:26])[n:25]1>>[CH2:1]([CH2:2][CH3:3])[P:4](=[O:5])([CH2:6][CH2:7][CH3:8])[c:9]1[cH:10][cH:11][c:12]([NH:15][c:17]2[c:18]3[n:19][cH:20][n:21]([CH:27]4[O:28][CH2:29][CH2:30][CH2:31][CH2:32]4)[c:22]3[n:23][c:24]([I:26])[n:25]2)[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-294cf2868d91439cb0879f80db1676a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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