Hydrochloric Acid → Hydrochloric Acid

HRID 1224146Notes

Reaction equation

HRID 1224146 reaction equation
[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13](-[c:18]4[cH:19][n:20][c:21]([C:23]5([NH:27][S:28]([C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:24][CH2:25][CH2:26]5)[s:22]4)[cH:14][c:15]([CH3:17])[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1.[ClH:34].[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1>>[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13](-[c:18]4[cH:19][n:20][c:21]([C:23]5([NH2:27])[CH2:24][CH2:25][CH2:26]5)[s:22]4)[cH:14][c:15]([CH3:17])[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1.[ClH:34]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 67247850N-[1-(5-{3-[(4-cyclopropylpyrimidin-2-yl)amino]-5-methylphenyl}-1,3-thiazol-2-yl)cyclobutyl]-2-methylpropane-2-sulfinamide

Product 2

HCID 313Hydrochloric AcidHCID 58456299US8759366, N-{3-[2-(1-aminocyclobutyl)-1,3-thiazol-5-yl]-5-methylphenyl}-4-cyclopropyl-pyrimidin-2-amine hydrochloride

Sources & evidence

ORD record
ord-c39464232fe642f1a95acc5f47645c23
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…