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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1224240Generated: October 27, 2026

1-(4-Bromo-phenyl)-2,2-difluoro-propan-1-ol → 2-(4-(2,2-Difluoro-1-hydroxypropyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/1224240

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromo-phenyl)-2,2-difluoro-propan-1-olHCID 23729514—
Reactant8-(3,3-Dimethyl-butyryl)-2-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577894—
Reactant8-(3,3-Dimethyl-butyryl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59578014—
Product2-(4-(2,2-Difluoro-1-hydroxypropyl)phenyl)-8-(3,3-dimethylbutanoyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59577905—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-e9a47187fc7d45e689e6facdfaccbcfe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)