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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1224280Generated: November 1, 2026

Tetrahydrofuran → Di-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate

https://huagongshe.com/reaction/1224280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantIsobutyl chloroformateHCID 62365—
Reactant1,4-Di-Boc-piperazine-2-carboxylic acidHCID 11255979—
ProductDi-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylateHCID 22711445—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-47b91612ed5940bfbbdabccdcee2b93e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)