Water → tert-Butyl 3-((tosyloxy)methyl)pyrrolidine-1-carboxylate

HRID 1224563Notes

Reaction equation

HRID 1224563 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH:21]([CH2:24][OH:25])[CH2:22][CH2:23]1.[OH2:26].[c:1]1([CH3:11])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[Cl:10])[cH:5][cH:6]1.[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[c:1]1([CH3:11])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[O:25][CH2:24][CH:21]2[CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:23][CH2:22]2)[cH:5][cH:6]1

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 5237175tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 20067158tert-Butyl 3-((tosyloxy)methyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-c14da62499034bcebd51b197ca4c25d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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