Dimethyl Sulfoxide → 5-[9-(Cyclopropylmethyl)-6-morpholin-4-yl-8-piperazin-1-yl-9H-purin-2-yl]pyrimidin-2-amine
Reaction equation
[CH2:32]1[CH2:33][NH:34][CH2:35][CH2:36][NH:37]1.[CH3:1][S:2](=[O:3])[CH3:4].[CH3:38][OH:39].[Cl:40][CH2:41][Cl:42].[Cl:5][c:6]1[n:7]([CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:8]2[n:9][c:10](-[c:21]3[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]3)[n:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:13]2[n:14]1>>[c:6]1([N:34]2[CH2:33][CH2:32][NH:37][CH2:36][CH2:35]2)[n:7]([CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:8]2[n:9][c:10](-[c:21]3[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]3)[n:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:13]2[n:14]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b2ee629084a44414942fbaba3991590c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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