Hydrochloric Acid → 6-(Piperidin-4-yloxy)-benzo[b]thiophene-2-carboxylic acid ethyl ester

HRID 1224870Notes

Reaction equation

HRID 1224870 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][cH:17][c:18]3[c:19]([s:20][c:21]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:22]3)[cH:28]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36].[ClH:29].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][cH:17][c:18]3[c:19]([s:20][c:21]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:22]3)[cH:28]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8900HeptaneHCID 312751,4-DioxaneHCID 687265814-(2-Ethoxycarbonyl-benzo[b]thiophen-6-yloxy)-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 688803516-(Piperidin-4-yloxy)-benzo[b]thiophene-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-6d427c26ab9b4db0be202107e9dfbc7c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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