Methanol → (2-Chloro-4-(tetrahydro-pyran-2-yloxy)-benzyl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine
Reaction equation
[BH4-:38].[CH2:40]([Cl:41])[Cl:42].[CH3:43][OH:44].[Cl:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][c:8]([O:10][CH:11]2[O:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:9]1.[Mg+2:32].[N:17]1([CH2:22][CH2:23][O:24][c:25]2[cH:26][cH:27][c:28]([NH2:31])[cH:29][cH:30]2)[CH2:18][CH2:19][CH2:20][CH2:21]1.[Na+:39].[O-:33][S:34](=[O:35])(=[O:36])[O-:37]>>[Cl:1][c:2]1[c:3]([CH2:4][NH:31][c:28]2[cH:27][cH:26][c:25]([O:24][CH2:23][CH2:22][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:30][cH:29]2)[cH:6][cH:7][c:8]([O:10][CH:11]2[O:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:9]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-7667194d1a824098a6bd7f897c6d75b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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