Isatin → 1-(diphenylmethyl)-4-fluoro-3-hydroxy-3-(7-hydroxy-2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-dihydro-2H-indol-2-one
Reaction equation
[CH3:12][c:13]1[s:14][c:15]2[cH:16][cH:17][c:18]([OH:19])[cH:20][c:21]2[n:22]1.[O:1]1[c:2]2[c:3]([cH:7][c:8]([OH:11])[cH:9][cH:10]2)[O:4][CH2:5][CH2:6]1.[O:48]=[C:49]1[C:50](=[O:51])[c:52]2[c:53]([cH:54][cH:55][cH:56][cH:57]2)[NH:58]1.[c:23]1([CH:29]([N:30]2[C:31](=[O:41])[C:32](=[O:40])[c:33]3[c:34]([F:39])[cH:35][cH:36][cH:37][c:38]32)[c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[O:1]1[c:2]2[c:3]([cH:7][c:8]([OH:11])[c:9]([C:32]3([OH:40])[C:31](=[O:41])[N:30]([CH:29]([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[c:42]4[cH:43][cH:44][cH:45][cH:46][cH:47]4)[c:38]4[c:33]3[c:34]([F:39])[cH:35][cH:36][cH:37]4)[cH:10]2)[O:4][CH2:5][CH2:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-651b0a9486d1469d82bc824c57495de7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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