Methanol → tert-Butyl 4-(4-aminobenzyl)-2-methylpiperazine-1-carboxylate

HRID 1225257Notes

Reaction equation

HRID 1225257 reaction equation
[CH3:1][CH:2]1[N:3]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:4][CH2:5][N:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([N+:15]([O-:16])=[O:17])[cH:13][cH:14]2)[CH2:7]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][OH:33]>>[CH3:1][CH:2]1[N:3]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:4][CH2:5][N:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([NH2:15])[cH:13][cH:14]2)[CH2:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8471TriethylamineHCID 178430372tert-butyl 2-methyl-4-[(4-nitrophenyl)methyl]piperazine-1-carboxylate

Product 1

HCID 72264407tert-Butyl 4-(4-aminobenzyl)-2-methylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-02123fed1587489d94101fe63369ec02
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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