Dichloromethane → 8-Cyclopropyl-4-(3-imidazol-1-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:17][C:18]([CH2:19][C:20](=[O:5])[c:22]2[cH:23][c:24](-[n:28]3[cH:29][n:30][cH:31][cH:32]3)[cH:25][cH:26][cH:27]2)=[O:33])[cH:10][c:11]([CH:14]2[CH2:15][CH2:16]2)[cH:12][cH:13]1)([CH3:6])([CH3:21])[CH3:34].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[N:7]1=[C:20]([c:22]2[cH:23][c:24](-[n:28]3[cH:29][n:30][cH:31][cH:32]3)[cH:25][cH:26][cH:27]2)[CH2:19][C:18](=[O:33])[NH:17][c:9]2[c:8]1[cH:13][cH:12][c:11]([CH:14]1[CH2:15][CH2:16]1)[cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-de9754c4f7dd4a01b91c7c2d357e8733
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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