Water → 2-[6-Amino-5-(2,2,2-trifluoro-ethoxy)-4'-trifluoromethyl-biphenyl-3-yl]-3-cyclobutyl-propionic acid Methyl Ester
Reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]1[CH2:7][CH2:8][CH2:9]1)[c:10]1[cH:11][c:12]([Br:23])[c:13]([NH2:22])[c:14]([O:16][CH2:17][C:18]([F:19])([F:20])[F:21])[cH:15]1)=[O:24].[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[CH3:45][O:46][CH2:47][CH2:48][O:49][CH3:50].[F:25][C:26]([c:27]1[cH:28][cH:29][c:30]([B:33]([OH:34])[OH:35])[cH:31][cH:32]1)([F:36])[F:37].[OH2:38].[cH:51]1[cH:52][cH:53][c:54]([P:55]([Pd:56]([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[P:95]([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)([c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[cH:126][cH:127]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]1[CH2:7][CH2:8][CH2:9]1)[c:10]1[cH:11][c:12](-[c:30]2[cH:29][cH:28][c:27]([C:26]([F:25])([F:36])[F:37])[cH:32][cH:31]2)[c:13]([NH2:22])[c:14]([O:16][CH2:17][C:18]([F:19])([F:20])[F:21])[cH:15]1)=[O:24]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5c58c7db07fe442f92281dff5a748f5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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