Trifluoroacetic acid → 6-(2,7-Diazaspiro[3.5]nonan-7-yl)-4-(5-methyl-1H-pyrazol-3-ylamino)-2-[2-{3-(pyrid-2-yl)isoxazol-5-yl}pyrrolidin-1-yl]pyrimidine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]2([CH2:11]1)[CH2:12][CH2:13][N:14]([c:17]1[cH:18][c:19]([NH:39][c:40]3[n:41][nH:42][c:43]([CH3:45])[cH:44]3)[n:20][c:21]([N:23]3[CH:24]([c:28]4[cH:29][c:30](-[c:33]5[n:34][cH:35][cH:36][cH:37][cH:38]5)[n:31][o:32]4)[CH2:25][CH2:26][CH2:27]3)[n:22]1)[CH2:15][CH2:16]2)([CH3:5])([CH3:6])[CH3:7].[F:46][C:47]([F:48])([F:49])[C:50]([OH:51])=[O:52]>>[NH:8]1[CH2:9][C:10]2([CH2:11]1)[CH2:12][CH2:13][N:14]([c:17]1[cH:18][c:19]([NH:39][c:40]3[n:41][nH:42][c:43]([CH3:45])[cH:44]3)[n:20][c:21]([N:23]3[CH:24]([c:28]4[cH:29][c:30](-[c:33]5[n:34][cH:35][cH:36][cH:37][cH:38]5)[n:31][o:32]4)[CH2:25][CH2:26][CH2:27]3)[n:22]1)[CH2:15][CH2:16]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4ca9f693b4a34ac2b3deb80b3c88f7a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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