Hydrochloric Acid → 1-[(4-Hydroxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid
Reaction equation
[CH3:31][C:32]([CH3:33])([O-:34])[CH3:35].[CH3:38][OH:39].[ClH:37].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:25](=[O:26])[O:27][CH3:28])[CH2:13][N:14]([C:16](=[O:17])[N:18]3[CH2:19][CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]3)[CH2:15]2)[cH:8][cH:9]1)([F:29])[F:30].[K+:36].[OH2:40]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:25](=[O:26])[OH:27])[CH2:13][N:14]([C:16](=[O:17])[N:18]3[CH2:19][CH2:20][CH:21]([OH:24])[CH2:22][CH2:23]3)[CH2:15]2)[cH:8][cH:9]1)([F:29])[F:30]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f22972664ba447e48ae267c59a021732
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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