Hydrochloric Acid → 5-benzyloxy-8-fluoro-N-(6-isopropylpyridin-3-yl)-N-{[1-(2-pyridylmethyl)pyrazol-4-yl]methyl}-1,2,3,4-tetrahydronaphthalene-1-carboxamide

HRID 1225824Notes

Reaction equation

HRID 1225824 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([c:16]([F:19])[cH:17][cH:18]1)[CH:14]([C:20](=[O:21])[N:22]([CH2:23][c:24]1[cH:25][n:26][nH:27][cH:28]1)[c:29]1[cH:30][n:31][c:32]([CH:35]([CH3:36])[CH3:37])[cH:33][cH:34]1)[CH2:13][CH2:12][CH2:11]2.[Cl:39][CH2:40][c:41]1[n:42][cH:43][cH:44][cH:45][cH:46]1.[ClH:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([c:16]([F:19])[cH:17][cH:18]1)[CH:14]([C:20](=[O:21])[N:22]([CH2:23][c:24]1[cH:25][n:26]([CH2:40][c:41]3[n:42][cH:43][cH:44][cH:45][cH:46]3)[n:27][cH:28]1)[c:29]1[cH:30][n:31][c:32]([CH:35]([CH3:36])[CH3:37])[cH:33][cH:34]1)[CH2:13][CH2:12][CH2:11]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 23393Picolyl chlorideHCID 59597342HCID 59597342, compound

Product 1

HCID 178541635-benzyloxy-8-fluoro-N-(6-isopropylpyridin-3-yl)-N-{[1-(2-pyridylmethyl)pyrazol-4-yl]methyl}-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Sources & evidence

ORD record
ord-4f00aa41de1e405ba9e61ec768315744
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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