Tetrahydrofuran → 8-(1-((3,5-difluorophenyl)(methyl)amino)ethyl)-N-(2-hydroxyethyl)-N-methyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide
Reaction equation
[C:19]([Si:20]([c:21]1[cH:22][cH:23][cH:60][cH:61][cH:62]1)([O:24][CH2:25][CH2:26][N:27]([C:28](=[O:29])[c:30]1[cH:31][c:32]2[c:33](=[O:58])[cH:34][c:35]([N:52]3[CH2:53][CH2:54][O:55][CH2:56][CH2:57]3)[o:36][c:37]2[c:38]([CH:40]([CH3:41])[N:42]([CH3:43])[c:44]2[cH:45][c:46]([F:51])[cH:47][c:48]([F:50])[cH:49]2)[cH:39]1)[CH3:59])[c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)([CH3:69])([CH3:70])[CH3:71].[CH2:72]1[O:73][CH2:74][CH2:75][CH2:76]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1]>>[OH:24][CH2:25][CH2:26][N:27]([C:28](=[O:29])[c:30]1[cH:31][c:32]2[c:33](=[O:58])[cH:34][c:35]([N:52]3[CH2:53][CH2:54][O:55][CH2:56][CH2:57]3)[o:36][c:37]2[c:38]([CH:40]([CH3:41])[N:42]([CH3:43])[c:44]2[cH:45][c:46]([F:51])[cH:47][c:48]([F:50])[cH:49]2)[cH:39]1)[CH3:59]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-68896d3bc7da443cb617e493a986afdb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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