Methanol → [4-(5-Hydroxy-5,6,7,8-tetrahydro-[1,8]naphthyridin-3-yl)phenyl]-(4-methylpiperazin-1-yl)methanone
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:9]([n:10][cH:11]1)[NH:8][CH2:7][CH2:6][CH:5]2[OH:12].[C:37]([O:38][CH2:39][CH3:40])(=[O:41])[CH3:42].[CH3:13][N:14]1[CH2:15][CH2:16][N:17]([C:20](=[O:21])[c:22]2[cH:23][cH:24][c:25]([B:28]3[O:29][C:30]([CH3:31])([CH3:32])[C:33]([CH3:34])([CH3:35])[O:36]3)[cH:26][cH:27]2)[CH2:18][CH2:19]1.[CH3:43][OH:44]>>[c:2]1(-[c:25]2[cH:24][cH:23][c:22]([C:20]([N:17]3[CH2:16][CH2:15][N:14]([CH3:13])[CH2:19][CH2:18]3)=[O:21])[cH:27][cH:26]2)[cH:3][c:4]2[c:9]([n:10][cH:11]1)[NH:8][CH2:7][CH2:6][CH:5]2[OH:12]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b5fd82cfb22c4633b1b92d19a0b79914
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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