Diisopropylethylamine → N-(4-(Difluoromethoxy)phenyl)-5,6,7,8-tetrahydro-7-(3-(methylsulfonyl)pyridin-2-yl)pyrido[3,4-d]pyrimidin-4-amine
Reaction equation
[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:22][c:23]1[n:24][cH:25][cH:26][cH:27][c:28]1[S:29](=[O:30])(=[O:31])[CH3:32].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([NH:10][c:11]2[c:12]3[c:13]([n:14][cH:15][n:16]2)[CH2:17][NH:18][CH2:19][CH2:20]3)[cH:8][cH:9]1)[F:21]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([NH:10][c:11]2[c:12]3[c:13]([n:14][cH:15][n:16]2)[CH2:17][N:18]([c:23]2[n:24][cH:25][cH:26][cH:27][c:28]2[S:29](=[O:30])(=[O:31])[CH3:32])[CH2:19][CH2:20]3)[cH:8][cH:9]1)[F:21]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-dc0a0b1e12f74466b5f8599e4a5aab57
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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