Hydrochloric Acid → N-(4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide

HRID 1226725Notes

Reaction equation

HRID 1226725 reaction equation
[CH3:1][C:2]1([CH3:23])[CH2:3][C:4](=[O:22])[NH:5][c:6]2[cH:7][c:8]([NH:12][C:13]([c:14]3[c:15]([F:20])[n:16][cH:17][cH:18][cH:19]3)=[O:21])[cH:9][cH:10][c:11]21.[ClH:24].[ClH:25].[nH:26]1[cH:27][cH:28][c:29]2[c:30]1[n:31][cH:32][cH:33][c:34]2[CH2:35][NH2:36]>>[CH3:1][C:2]1([CH3:23])[CH2:3][C:4](=[O:22])[NH:5][c:6]2[cH:7][c:8]([NH:12][C:13]([c:14]3[c:15]([NH:36][CH2:35][c:34]4[c:29]5[cH:28][cH:27][nH:26][c:30]5[n:31][cH:32][cH:33]4)[n:16][cH:17][cH:18][cH:19]3)=[O:21])[cH:9][cH:10][c:11]21

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 11679841(1H-Pyrrolo[2,3-b]pyridin-4-yl)methanamineHCID 21961472N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide

Product 1

HCID 58941984N-(4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide

Sources & evidence

ORD record
ord-8ecc0f0b12ca4940a48fa2a147585291
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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