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HRID12268

反应详情

EQUATION

反应方程式

HRID 12268 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)C(=O)C(=O)OCC
HCID69105

Propanedioic acid, oxo-, diethyl ester

C7H10O5

结构：CCNc1nccc(C(C)=O)n1
HCID68452125

未命名化合物

PRODUCTS

生成物

1
结构：CCNc1nccc(C(=O)CC(O)(C(=O)OCC)C(=O)OCC)n1
HCID68452836

未命名化合物

CONDITIONS

反应条件

温度
110 °C

PROCEDURE

实验过程

A mixture consisting of 1.9 g of 1-(2-ethylaminopyrimidin-4-yl)ethanone and 1.86 ml of diethyl ketomalonate is heated at 110° C. for 18 hours. The mixture is purified by column chromatography (silica gel, mobile phase:methylene chloride:methanol=98:2).

WORKUP

后处理

  1. customThe mixture is purified by column chromatography (silica gel, mobile phase:methylene chloride:methanol=98:2)