Water → tert-Butyl 4-(3-hydroxypropyl)tetrahydro-1(2h)-pyridinecarboxylate

HRID 1226816Notes

Reaction equation

[BH3:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][C:16](=[O:17])[OH:18])[CH2:12][CH2:13]1.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[OH2:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][CH2:16][OH:17])[CH2:12][CH2:13]1

Participants

Reactant 4

HCID 962Water

HCID 6331Borane

HCID 8028Tetrahydrofuran

HCID 15125403-(1-((Tert-butoxy)carbonyl)piperidin-4-yl)propanoic acid

Product 1

HCID 2800739tert-Butyl 4-(3-hydroxypropyl)tetrahydro-1(2h)-pyridinecarboxylate

Sources & evidence

ORD record: ord-66912419a4ec415c81d7a49fb117a565
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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