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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1226947Generated: November 2, 2026

Dimethylformamide → N-[1-[4-hydroxy-4-(2-propan-2-yl-1,3-thiazol-5-yl)cyclohexyl]pyrrolidin-3-yl]-4-oxo-4-[3-(trifluoromethyl)phenyl]butanamide

https://huagongshe.com/reaction/1226947

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
Reactant4-Oxo-4-(3-trifluoromethylphenyl)butyric acidHCID 13408836—
Reactant4-(3-Aminopyrrolidin-1-yl)-1-(2-propan-2-yl-1,3-thiazol-5-yl)cyclohexan-1-olHCID 57896442—
ProductN-[1-[4-hydroxy-4-(2-propan-2-yl-1,3-thiazol-5-yl)cyclohexyl]pyrrolidin-3-yl]-4-oxo-4-[3-(trifluoromethyl)phenyl]butanamideHCID 57896463—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-00317af14cce4b8e9c02dcb6fdb2f992
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)