Dimethylformamide → N-[1-[4-hydroxy-4-(2-propan-2-yl-1,3-thiazol-5-yl)cyclohexyl]pyrrolidin-3-yl]-4-oxo-4-[3-(trifluoromethyl)phenyl]butanamide
Reaction equation
[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[NH2:1][CH:2]1[CH2:3][N:4]([CH:7]2[CH2:8][CH2:9][C:10]([OH:13])([c:14]3[cH:15][n:16][c:17]([CH:19]([CH3:20])[CH3:21])[s:18]3)[CH2:11][CH2:12]2)[CH2:5][CH2:6]1.[O:22]=[C:23]([CH2:24][CH2:25][C:26](=[O:27])[OH:28])[c:29]1[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[NH:1]([CH:2]1[CH2:3][N:4]([CH:7]2[CH2:8][CH2:9][C:10]([OH:13])([c:14]3[cH:15][n:16][c:17]([CH:19]([CH3:20])[CH3:21])[s:18]3)[CH2:11][CH2:12]2)[CH2:5][CH2:6]1)[C:26]([CH2:25][CH2:24][C:23](=[O:22])[c:29]1[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]1)=[O:27]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-00317af14cce4b8e9c02dcb6fdb2f992
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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