Trifluoroacetic acid → (2,3,4,5-Tetrahydro-1H-3-benzazepin-7-yl)-[8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amine

HRID 1227008Notes

Reaction equation

HRID 1227008 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([NH:19][c:20]3[n:21][n:22]4[c:23]([c:24](-[c:28]5[cH:29][c:30]([C:34]([F:35])([F:36])[F:37])[cH:31][cH:32][cH:33]5)[cH:25][cH:26][cH:27]4)[n:38]3)[cH:18]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[OH:39][C:40]([C:41]([F:42])([F:43])[F:44])=[O:45]>>[NH:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][cH:16][c:17]([NH:19][c:20]3[n:21][n:22]4[c:23]([c:24](-[c:28]5[cH:29][c:30]([C:34]([F:35])([F:36])[F:37])[cH:31][cH:32][cH:33]5)[cH:25][cH:26][cH:27]4)[n:38]3)[cH:18]2)[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 596125237-[8-(3-Trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamino]-1,2,4,5-tetrahydro-3-benzazepine-3-carboxylic acid tert-butyl ester

Product 1

HCID 59612552(2,3,4,5-Tetrahydro-1H-3-benzazepin-7-yl)-[8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amine

Sources & evidence

ORD record
ord-6be50c80ff334d4eaa38882732d9cbe3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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