Dimethyl Sulfoxide → 4-Chloro-6-(2,6-difluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbonitrile
Reaction equation
[CH3:24][S:25]([CH3:26])=[O:27].[CH3:28][CH2:29][O:30][C:31]([CH3:32])=[O:33].[Cl:12][c:13]1[n:14][c:15]([S:22][CH3:23])[n:16][c:17]([Cl:21])[c:18]1[C:19]#[N:20].[F:1][c:2]1[c:3]([NH2:4])[c:5]([F:9])[cH:6][cH:7][cH:8]1.[H-:11].[Na+:10]>>[F:1][c:2]1[c:3]([NH:4][c:17]2[n:16][c:15]([S:22][CH3:23])[n:14][c:13]([Cl:12])[c:18]2[C:19]#[N:20])[c:5]([F:9])[cH:6][cH:7][cH:8]1Participants
7
Sources & evidence
- ORD record
- ord-05ff5dddc1654439996e021770b50b14
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…