Dimethylformamide → 9-Cyclopropyl-6-fluoro-7-(2-(pyridin-2-YL)ethynyl)isothiazolo[5,4-B]quinoline-3,4(2H,9H)-dione
Reaction equation
[Br:1][c:2]1[c:3]([F:20])[cH:4][c:5]2[c:6](=[O:19])[c:7]3[c:8]([n:9]([CH:12]4[CH2:13][CH2:14]4)[c:10]2[cH:11]1)[s:15][nH:16][c:17]3=[O:18].[C:21](#[CH:22])[c:23]1[n:24][cH:25][cH:26][cH:27][cH:28]1.[CH:29]([NH:30][CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[c:2]1([C:22]#[C:21][c:23]2[n:24][cH:25][cH:26][cH:27][cH:28]2)[c:3]([F:20])[cH:4][c:5]2[c:6](=[O:19])[c:7]3[c:8]([n:9]([CH:12]4[CH2:13][CH2:14]4)[c:10]2[cH:11]1)[s:15][nH:16][c:17]3=[O:18]Participants
5
Sources & evidence
- ORD record
- ord-e5317c565ba84d18acdc09472b936735
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…