tert-Butanol → [2-Methoxy-4-(4-morpholin-4-yl-piperidin-1-yl)-phenyl]-(7-pyridin-3-yl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-amine
Reaction equation
[C:51]([OH:52])([CH3:53])([CH3:54])[CH3:55].[CH3:1][O:2][c:3]1[c:4]([NH2:21])[cH:5][cH:6][c:7]([N:9]2[CH2:10][CH2:11][CH:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[CH2:13][CH2:14]2)[cH:8]1.[CH3:22][S:23](=[O:24])[c:25]1[n:26][n:27]2[c:28]([cH:29][n:30]1)[cH:31][cH:32][c:33]2-[c:34]1[cH:35][n:36][cH:37][cH:38][cH:39]1.[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cs+:41].[F-:40]>>[CH3:1][O:2][c:3]1[c:4]([NH:21][c:25]2[n:26][n:27]3[c:28]([cH:29][n:30]2)[cH:31][cH:32][c:33]3-[c:34]2[cH:35][n:36][cH:37][cH:38][cH:39]2)[cH:5][cH:6][c:7]([N:9]2[CH2:10][CH2:11][CH:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[CH2:13][CH2:14]2)[cH:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d9b859ab7583491e9274cc46eacf0029
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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