Dichloromethane → Trifluoroacetic acid

HRID 1227503Notes

Reaction equation

HRID 1227503 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([N:20]([S:21](=[O:22])(=[O:23])[CH3:24])[CH3:25])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:26][CH2:27][Cl:28].[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35]>>[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35].[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([N:20]([S:21](=[O:22])(=[O:23])[CH3:24])[CH3:25])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67553893N-[2-(1-t-Butoxycarbonylpiperidin-4-yl)phenyl]-N-methylmethanesulfonamide

Product 2

HCID 6422Trifluoroacetic acidHCID 86753992N-methyl-N-(2-piperidin-4-ylphenyl)methanesulfonamide

Sources & evidence

ORD record
ord-40204e23040148e3904f4b5e0c469d8b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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