1,2-Dichloroethane → 5-Chloro-7-morpholin-4-yl-2-(3-morpholin-4-yl-azetidin-1-ylmethyl)-thiazolo[4,5-d]pyrimidine

HRID 1227573Notes

Reaction equation

HRID 1227573 reaction equation
[C:29]([O:30][BH-:31]([O:32][C:33](=[O:34])[CH3:35])[O:36][C:37](=[O:38])[CH3:39])(=[O:40])[CH3:41].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[n:8][c:9]([CH:11]=[O:12])[s:10]2.[Cl:43][CH2:44][CH2:45][Cl:46].[NH:19]1[CH2:20][CH:21]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[CH2:22]1.[Na+:42]>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[n:8][c:9]([CH2:11][N:19]1[CH2:20][CH:21]([N:23]3[CH2:24][CH2:25][O:26][CH2:27][CH2:28]3)[CH2:22]1)[s:10]2

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 923Sodium ionHCID 2724942TriacetoxyborohydrideHCID 134019734-(Azetidin-3-yl)morpholineHCID 576853925-Chloro-7-morpholinothiazolo[4,5-d]pyrimidine-2-carbaldehyde

Product 1

HCID 596060455-Chloro-7-morpholin-4-yl-2-(3-morpholin-4-yl-azetidin-1-ylmethyl)-thiazolo[4,5-d]pyrimidine

Sources & evidence

ORD record
ord-cfb2e9ca44154f4e9ddf47ff88177fdd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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