Hydrochloric Acid → 4-{6-Methoxy-7-[3-(4-methyl-piperazin-1-yl)-propoxy]-quinazolin-4-yl}-piperidine-1-carboxylic acid (4-morpholin-4-yl-phenyl)-amide
Reaction equation
[C:1]([O:2][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][N:30]4[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)([CH3:3])([CH3:4])[CH3:5].[ClH:37].[N+:38]([c:39]1[cH:40][cH:41][c:42]([O:43][C:44](=[O:45])[NH:49][c:50]2[cH:51][cH:52][c:53]([N:56]3[CH2:57][CH2:58][O:59][CH2:60][CH2:61]3)[cH:54][cH:55]2)[cH:46][cH:47]1)([O-:48])=[O:62]>>[C:6](=[O:7])([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][N:30]4[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:49][c:50]1[cH:51][cH:52][c:53]([N:56]2[CH2:57][CH2:58][O:59][CH2:60][CH2:61]2)[cH:54][cH:55]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-915086629c29450d97014af845eb02b2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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