Hydrochloric Acid → 5-Chloro-2-[1-[3-(4-chlorophenyl)piperidin-4-yl]ethoxy]pyridine

HRID 1227901Notes

Reaction equation

HRID 1227901 reaction equation
[CH2:24]([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[N:31]1[CH2:32][CH:33]([c:47]2[cH:48][cH:49][c:50]([Cl:53])[cH:51][cH:52]2)[CH:34]([CH:37]([CH3:38])[O:39][c:40]2[n:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[CH2:35][CH2:36]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH:13]2[c:14]2[cH:15][cH:16][c:17]([Cl:18])[cH:19][cH:20]2)[n:21][cH:22]1.[ClH:23]>>[NH:31]1[CH2:32][CH:33]([c:47]2[cH:48][cH:49][c:50]([Cl:53])[cH:51][cH:52]2)[CH:34]([CH:37]([CH3:38])[O:39][c:40]2[n:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[CH2:35][CH2:36]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 684715562-{(SR)-1-[(3SR,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethoxy}-5-chloro-pyridineHCID 712055575-chloro-2-[(3RS, 4RS)-3-(4-chloro-phenyl)-piperidin-4-ylmethoxy]-pyridine

Product 1

HCID 684720515-Chloro-2-[1-[3-(4-chlorophenyl)piperidin-4-yl]ethoxy]pyridine

Sources & evidence

ORD record
ord-bb6040b3eadc454ab0ac8c1d47b23841
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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