Dichloromethane → 2-(2-bromo-acetylamino)-5-[3-(2-methoxy-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N,N-dimethyl-benzamide
Reaction equation
[Br:47][CH2:48][C:49](=[O:50])[Cl:51].[CH:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH2:43][CH3:44])([CH3:45])[CH3:46].[Cl:52][CH2:53][Cl:54].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([CH3:7])[CH3:8])[cH:9][c:10](-[c:13]2[cH:14][c:15]3[c:16]([n:17][cH:18]2)[n:19]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[n:20][c:21]3-[c:22]2[c:23]([O:28][CH3:29])[cH:24][cH:25][cH:26][cH:27]2)[cH:11][cH:12]1>>[NH:1]([c:2]1[c:3]([C:4](=[O:5])[N:6]([CH3:7])[CH3:8])[cH:9][c:10](-[c:13]2[cH:14][c:15]3[c:16]([n:17][cH:18]2)[n:19]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[n:20][c:21]3-[c:22]2[c:23]([O:28][CH3:29])[cH:24][cH:25][cH:26][cH:27]2)[cH:11][cH:12]1)[C:49]([CH2:48][Br:47])=[O:50]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0b76c6a1dc7842f1b54d18fd1d040773
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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