Sodium ion → 4-imidazol-1-yl-2,3,3-trimethyl-3,4-dihydro-2H-isoquinolin-1-one

HRID 1228023Notes

Reaction equation

HRID 1228023 reaction equation
[CH3:21][I:22].[H-:20].[Na+:19].[O:23]=[CH:24][N:25]([CH3:26])[CH3:27].[n:1]1([CH:6]2[C:7]([CH3:17])([CH3:18])[NH:8][C:9](=[O:16])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]32)[cH:2][n:3][cH:4][cH:5]1>>[n:1]1([CH:6]2[C:7]([CH3:17])([CH3:18])[N:8]([CH3:21])[C:9](=[O:16])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]32)[cH:2][n:3][cH:4][cH:5]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 166653HydrideHCID 577811054-Imidazol-1-yl-3,3-dimethyl-2,4-dihydroisoquinolin-1-one

Product 1

HCID 577811164-imidazol-1-yl-2,3,3-trimethyl-3,4-dihydro-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-0b9ed51eeadb4326b6f8d966c0eb60a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…