Diethyl Ether → 8-Chloro-5,7-dimethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-6-ol

HRID 122809Notes

Reaction equation

HRID 122809 reaction equation
[CH2:28]([O:29][CH2:30][CH3:31])[CH3:32].[CH3:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([CH3:13])[c:11]1[OH:12])[O:7][C:6]1([CH2:5][CH2:4]2)[CH2:14][CH2:15][CH2:16]1.[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[S:17]([Cl:18])(=[O:19])([Cl:20])=[O:21]>>[CH3:1][c:2]1[c:3]2[c:8]([c:9]([Cl:20])[c:10]([CH3:13])[c:11]1[OH:12])[O:7][C:6]1([CH2:5][CH2:4]2)[CH2:14][CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 8857Ethyl AcetateHCID 24648Sulfuryl chlorideHCID 115502985,7-Dimethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-6-ol

Product 1

HCID 578035038-Chloro-5,7-dimethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-6-ol

Sources & evidence

ORD record
ord-f5f2d541d9eb48f7bc47eee744b0b6c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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