Methanol → Trifluoroacetic acid

HRID 1228140Notes

Reaction equation

HRID 1228140 reaction equation
[CH3:32][OH:33].[CH3:8][CH:9]([CH2:10][O:11][CH3:12])[O:13][c:14]1[n:15][c:16]([NH2:31])[c:17]2[n:18][c:19]([O:29][CH3:30])[n:20]([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][O:28]3)[c:21]2[n:22]1.[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7]>>[CH3:8][CH:9]([CH2:10][O:11][CH3:12])[O:13][c:14]1[n:15][c:16]([NH2:31])[c:17]2[n:18][c:19]([O:29][CH3:30])[nH:20][c:21]2[n:22]1.[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7]

Participants

5

Reactant 3

HCID 887MethanolHCID 6422Trifluoroacetic acidHCID 576997482-{[1-methyl-2-(methoxy)ethyl]oxy}-8-(methoxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Product 2

HCID 6422Trifluoroacetic acidHCID 1784955408-methoxy-2-(1-methoxypropan-2-yloxy)-7H-purin-6-amine

Sources & evidence

ORD record
ord-61dfe99368ba45ce81c88f0e19b69928
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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