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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1228281Generated: October 31, 2026

2-Methylspiro[isoindoline-3,4'-piperidine]-1-one → 2-Methyl-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)spiro[isoindoline-1,4'-piperidin]-3-one

https://huagongshe.com/reaction/1228281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylspiro[isoindoline-3,4'-piperidine]-1-oneHCID 12112518—
Reactant2-(Trifluoromethyl)benzenepropanoic acidHCID 15284809—
Product2-Methyl-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)spiro[isoindoline-1,4'-piperidin]-3-oneHCID 58295689—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-cb4e55091b4848e899105dd58a363e17
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)