HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid (2-amino-phenyl)amide → 4-(1H-Benzimidazol-2-yl)-6-chloro-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid (2-amino-phenyl)amide | HCID 86611609 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-(1H-Benzimidazol-2-yl)-6-chloro-2H-pyridazin-3-one | HCID 135978781 | — |
Reaction Steps
A solution of 26.4 g of 6-chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid (2-aminophenyl)amide in 500 ml of acetic acid is stirred at 110° C. for 2.5 hours and then the solvent is distilled off. The crude product obtained in this way is employed without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07727989B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-0a5a35357a4242119c12cf0fec91f87f |
| Source note | uspto-grants-2010_06 |