N,N'-Dimethylethylenediamine → 1-[3-Bromo-5-(pyridine-3-carbonyl)-phenyl]-pyrrolidin-2-one

HRID 1228493Notes

Reaction equation

HRID 1228493 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:9](=[O:10])[c:11]2[cH:12][n:13][cH:14][cH:15][cH:16]2)[cH:5][c:6]([Br:8])[cH:7]1.[C:17](=[O:18])([O-:19])[O-:20].[CH3:23][NH:24][CH2:25][CH2:26][NH:27][CH3:28].[Cs+:21].[Cs+:22].[Cu:35][I:36].[O:29]=[C:30]1[CH2:31][CH2:32][CH2:33][NH:34]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[c:2]1([N:34]2[C:30](=[O:29])[CH2:31][CH2:32][CH2:33]2)[cH:3][c:4]([C:9](=[O:10])[c:11]2[cH:12][n:13][cH:14][cH:15][cH:16]2)[cH:5][c:6]([Br:8])[cH:7]1

Participants

8

Reactant 7

HCID 8070N,N'-DimethylethylenediamineHCID 120252-PyrrolidoneHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 106649193-(3,5-Dibromobenzoyl)pyridine

Product 1

HCID 574709891-[3-Bromo-5-(pyridine-3-carbonyl)-phenyl]-pyrrolidin-2-one

Sources & evidence

ORD record
ord-4e82a53442594138aa815bf678b5fa69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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