Dichloromethane → 1-(3-Chlorophenyl)-2-(2-methoxyethoxy)-1-piperidin-3-ylethanol

HRID 1228555Notes

Reaction equation

HRID 1228555 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:8]([CH2:9][O:10][CH2:11][CH2:12][O:13][CH3:14])([OH:15])[CH:16]2[CH2:17][N:18]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:19][CH2:20][CH2:21]2)[cH:5][cH:6][cH:7]1.[Cl:36][CH2:37][Cl:38].[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35]>>[Cl:1][c:2]1[cH:3][c:4]([C:8]([CH2:9][O:10][CH2:11][CH2:12][O:13][CH3:14])([OH:15])[CH:16]2[CH2:17][NH:18][CH2:19][CH2:20][CH2:21]2)[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 72282995Tert-butyl 3-[1-(3-chlorophenyl)-1-hydroxy-2-(2-methoxyethoxy)ethyl]piperidine-1-carboxylate

Product 1

HCID 694715061-(3-Chlorophenyl)-2-(2-methoxyethoxy)-1-piperidin-3-ylethanol

Sources & evidence

ORD record
ord-17b79b2eba784bb7914c3f25d68bab74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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